Bisulfite sequencing
id:
bisulfite-sequencing-309-9137709
title:
Bisulfite sequencing
text:
Bisulfite sequencing (also known as bisulphite sequencing) is the use of bisulfite treatment of DNA before routine sequencing to determine the pattern of methylation. DNA methylation was the first discovered epigenetic mark, and remains the most studied. In animals it predominantly involves the addition of a methyl group to the carbon-5 position of cytosine residues of the dinucleotide CpG, and is implicated in repression of transcriptional activity. Treatment of DNA with bisulfite converts cyto
brand slug:
wiki
category slug:
encyclopedia
description:
Lab procedure detecting 5-methylcytosines in DNA
original url:
https://en.wikipedia.org/wiki/Bisulfite_sequencing
date created:
date modified:
2024-01-08T21:59:32Z
main entity:
{"identifier":"Q4087270","url":"https://www.wikidata.org/entity/Q4087270"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/en/c/c9/Wiki_Bisulfite_sequencing_Figure_1_small.png","width":690,"height":480}
fields total:
13
integrity:
15