BI 224436

id: bi-224436-193-7970606
title: BI 224436
text: BI 224436 was an investigational new drug under development for the treatment of HIV infection. BI 224436 is the first non-catalytic site integrase inhibitor (NCINI). It inhibits HIV replication via binding to a conserved allosteric pocket of the HIV integrase enzyme. This makes the drug distinct in its mechanism of action compared to raltegravir and elvitegravir, which bind at the catalytic site. In October 2011, Gilead Sciences purchased exclusive rights to develop BI 224436 and several relate
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/BI_224436
date created:
date modified: 2023-12-01T20:41:13Z
main entity: {"identifier":"Q4835750","url":"https://www.wikidata.org/entity/Q4835750"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/6e/BI_224436.svg","width":495,"height":495}
fields total: 13
integrity: 15

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