Berzosertib
id:
berzosertib-287-3797518
title:
Berzosertib
text:
Berzosertib is a drug originally invented by Vertex Pharmaceuticals and licensed to Merck KGaA, Darmstadt, Germany, for development. It acts as a potent inhibitor of the enzyme ataxia telangiectasia and Rad3 related (ATR) and with lower potency as an inhibitor of ATM serine/threonine kinase (ATM). These enzymes are both involved in detecting DNA damage as part of cell cycle checkpoints during cell division. By inhibiting their activity, berzosertib interferes with the ability of rapidly dividing
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Berzosertib
date created:
date modified:
2024-03-29T21:58:01Z
main entity:
{"identifier":"Q27089129","url":"https://www.wikidata.org/entity/Q27089129"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/a9/Berzosertib_structure.png","width":1744,"height":620}
fields total:
13
integrity:
15