BEN domain

id: ben-domain-192-4019865
title: BEN domain
text: In molecular biology, the BEN domain is a protein domain which is found in diverse proteins including: SMAR1, a tumour-suppressor MAR-binding protein that down-regulates Cyclin D1 expression by recruiting HDAC1-mSin3A co-repressor complex at Cyclin D1 promoter locus; SMAR1 is the target of prostaglandin A2 (PGA2) induced growth arrest. NACC1, a novel member of the POZ/BTB, but which varies from other proteins of this class in that it lacks the characteristic DNA-binding motif. Mod(mdg4) isoform
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/BEN_domain
date created:
date modified: 2024-01-02T21:15:35Z
main entity: {"identifier":"Q24744731","url":"https://www.wikidata.org/entity/Q24744731"}
image:
fields total: 13
integrity: 13

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