Base J
id:
base-j-189-2053888
title:
Base J
text:
β-D-Glucopyranosyloxymethyluracil or base J is a hypermodified nucleobase found in the DNA of kinetoplastids including the human pathogenic trypanosomes. It was discovered in 1993, in the trypanosome Trypanosoma brucei and was the first hypermodified nucleobase found in eukaryotic DNA; it has since been found in other kinetoplastids, including Leishmania.
Within these organisms Base J acts as a RNA polymerase II transcription terminator, with its removal in knockout cells being accompanied by a
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Base_J
date created:
2012-03-06T12:09:12Z
date modified:
2024-09-09T16:24:48Z
main entity:
{"identifier":"Q1532320","url":"https://www.wikidata.org/entity/Q1532320"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e4/D-glucopyranosyloxymethyluracil.svg","width":620,"height":385}
fields total:
13
integrity:
16