Bardoxolone methyl
id:
bardoxolone-methyl-249-13521911
title:
Bardoxolone methyl
text:
Bardoxolone methyl is an experimental and orally-bioavailable semi-synthetic triterpenoid, based on the scaffold of the natural product oleanolic acid. Pre-clinical studies indicate that the compound acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway. A phase 3 clinical trial evaluating bardoxolone methyl for the treatment of chronic kidney disease (CKD) was terminated in October 2012 after patients treated with the drug were found to have experienced a higher rate of
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Bardoxolone_methyl
date created:
date modified:
2023-11-07T13:48:47Z
main entity:
{"identifier":"Q4860208","url":"https://www.wikidata.org/entity/Q4860208"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/ff/Bardoxolone_methyl.svg","width":224,"height":138}
fields total:
13
integrity:
15