BACE1-AS
id:
bace1-as-191-3996267
title:
BACE1-AS
text:
BACE1-AS, also known as BACE1 antisense RNA, is a human gene at 11q23.3 encoding a long noncoding RNA molecule. It is transcribed from the opposite strand to BACE1 and is upregulated in patients with Alzheimer's disease. BACE1-AS regulates the expression of BACE1 by increasing BACE1 mRNA stability and generating additional BACE1 through a post-transcriptional feed-forward mechanism. By the same mechanism it also raises concentrations of beta amyloid, the main constituent of senile plaques. BACE1
brand slug:
wiki
category slug:
encyclopedia
description:
Non-coding RNA in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/BACE1-AS
date created:
date modified:
2024-03-16T23:06:54Z
main entity:
{"identifier":"Q4834493","url":"https://www.wikidata.org/entity/Q4834493"}
image:
fields total:
13
integrity:
14