Autophagy protein 5
id:
autophagy-protein-5-304-13072266
title:
Autophagy protein 5
text:
Autophagy protein 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on chromosome 6. It is an E3 ubi autophagic cell death. ATG5 is a key protein involved in the extension of the phagophoric membrane in autophagic vesicles. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-I conjugation to PE (phosphatidylethanolamine) to form LC3-II. ATG5 can also act as a pro-apoptotic molecule targeted to the mitochondria. Under low
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Autophagy_protein_5
date created:
date modified:
2024-04-15T09:48:02Z
main entity:
{"identifier":"Q18034312","url":"https://www.wikidata.org/entity/Q18034312"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/03/Ideogram_human_chromosome_6.svg","width":474,"height":189}
fields total:
13
integrity:
15