ATM serine/threonine kinase
id:
atm-serine-threonine-kinase-184-13904535
title:
ATM serine/threonine kinase
text:
ATM serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks, oxidative stress, topoisomerase cleavage complexes, splicing intermediates, R-loops and in some cases by single-strand DNA breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Several of these targets, including p53, CHK2, B
brand slug:
wiki
category slug:
encyclopedia
description:
Mammalian protein found in Homo sapiens
original url:
https://en.wikipedia.org/wiki/ATM_serine/threonine_kinase
date created:
2005-07-08T18:56:48Z
date modified:
2024-09-07T10:12:26Z
main entity:
{"identifier":"Q141591","url":"https://www.wikidata.org/entity/Q141591"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/53/ATM_00000.png","width":2100,"height":2100}
fields total:
13
integrity:
16