Argos (EGFR Inhibitor)
id:
argos-egfr-inhibitor-195-6061632
title:
Argos (EGFR Inhibitor)
text:
Argos is a secreted protein that is an inhibitor of the epidermal growth factor receptor (EGFR) pathway in Drosophila melanogaster. Argos inhibits the EGFR pathway by sequestering the EGFR ligand Spitz. Argos binds the epidermal growth factor domain of Spitz, preventing interaction between Spitz and EGFR. Argos does not directly interact with EGFR. Argos represents the first example of ligand sequestration as a mechanism of inhibition in the ErbB (EGFR) family.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein found in Drosophila melanogaster
original url:
https://en.wikipedia.org/wiki/Argos_(EGFR_Inhibitor)
date created:
date modified:
2022-10-17T10:32:41Z
main entity:
{"identifier":"Q29656628","url":"https://www.wikidata.org/entity/Q29656628"}
image:
fields total:
13
integrity:
14