Apolipoprotein B deficiency
id:
apolipoprotein-b-deficiency-238-8916979
title:
Apolipoprotein B deficiency
text:
Apolipoprotein B deficiency is an autosomal dominant disorder resulting from a missense mutation which reduces the affinity of apoB-100 for the low-density lipoprotein receptor. This causes impairments in LDL catabolism, resulting in increased levels of low-density lipoprotein in the blood. The clinical manifestations are similar to diseases produced by mutations of the LDL receptor, such as familial hypercholesterolemia. Treatment may include, niacin or statin or ezetimibe. It is also known as
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Apolipoprotein_B_deficiency
date created:
date modified:
2024-01-19T04:10:30Z
main entity:
{"identifier":"Q4780235","url":"https://www.wikidata.org/entity/Q4780235"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4e/Autosomal_dominant_-_en.svg","width":738,"height":1260}
fields total:
13
integrity:
15