APH-1

id: aph-1-304-6040585
title: APH-1
text: APH-1 is a protein gene product originally identified in the Notch signaling pathway in Caenorhabditis elegans as a regulator of the cell-surface localization of nicastrin. APH-1 homologs in other organisms, including humans, have since been identified as components of the gamma secretase complex along with the catalytic subunit presenilin and the regulatory subunits nicastrin and PEN-2. The gamma-secretase complex is a multimeric protease responsible for the intramembrane proteolysis of transme
brand slug: wiki
category slug: encyclopedia
description: Protein gene product
original url: https://en.wikipedia.org/wiki/APH-1
date created:
date modified: 2022-04-08T20:59:36Z
main entity: {"identifier":"Q24788333","url":"https://www.wikidata.org/entity/Q24788333"}
image:
fields total: 13
integrity: 14

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