AP site
id:
ap-site-239-15425500
title:
AP site
text:
In biochemistry and molecular genetics, an AP site, also known as an abasic site, is a location in DNA that has neither a purine nor a pyrimidine base, either spontaneously or due to DNA damage. It has been estimated that under physiological conditions 10,000 apurinic sites and 500 apyrimidinic may be generated in a cell daily. AP sites can be formed by spontaneous depurination, but also occur as intermediates in base excision repair. In this process, a DNA glycosylase recognizes a damaged base
brand slug:
wiki
category slug:
encyclopedia
description:
Biochemical site of damaged DNA or RNA
original url:
https://en.wikipedia.org/wiki/AP_site
date created:
date modified:
2023-05-31T18:56:05Z
main entity:
{"identifier":"Q176783","url":"https://www.wikidata.org/entity/Q176783"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/7a/Site_AP.gif","width":298,"height":186}
fields total:
13
integrity:
15