AP endonuclease
id:
ap-endonuclease-240-11133663
title:
AP endonuclease
text:
Apurinic/apyrimidinic (AP) endonuclease is an enzyme that is involved in the DNA base excision repair pathway (BER). Its main role in the repair of damaged or mismatched nucleotides in DNA is to create a nick in the phosphodiester backbone of the AP site created when DNA glycosylase removes the damaged base. There are four types of AP endonucleases that have been classified according to their mechanism and site of incision. Class I AP endonucleases (EC 4.2.99.18) cleave 3′ to AP sites by a β-lya
brand slug:
wiki
category slug:
encyclopedia
description:
Enzyme involved in DNA repair
original url:
https://en.wikipedia.org/wiki/AP_endonuclease
date created:
date modified:
2021-09-24T22:55:24Z
main entity:
{"identifier":"Q4653506","url":"https://www.wikidata.org/entity/Q4653506"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4c/ApEndonuclease1.jpg","width":2880,"height":1494}
fields total:
13
integrity:
15