Amidophosphoribosyltransferase
id:
amidophosphoribosyltransferase-259-10759681
title:
Amidophosphoribosyltransferase
text:
Amidophosphoribosyltransferase (ATase), also known as glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an enzyme responsible for catalyzing the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA), using the amine group from a glutamine side-chain. This is the committing step in de novo purine synthesis. In humans it is encoded by the PPAT gene. ATase is a member of the purine/pyrimidine phosphoribosyltransferase family.
brand slug:
wiki
category slug:
encyclopedia
description:
Mammalian protein found in Homo sapiens
original url:
https://en.wikipedia.org/wiki/Amidophosphoribosyltransferase
date created:
date modified:
2023-08-26T13:07:53Z
main entity:
{"identifier":"Q408291","url":"https://www.wikidata.org/entity/Q408291"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/68/ATase_crystal_structure.png","width":640,"height":480}
fields total:
13
integrity:
15