AMG-517
id:
amg-517-253-8097848
title:
AMG-517
text:
AMG-517 is a drug which acts as a potent and selective blocker of the TRPV1 ion channel. It was developed as a potential treatment for chronic pain, but while it was an effective analgesic in animal studies it was dropped from human clinical trials at Phase I due to producing hyperthermia as a side effect, as well as poor water solubility. It is still used in scientific research into the function of the TRPV1 channel and its role in pain and inflammation, and has been used as a template for the
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/AMG-517
date created:
date modified:
2024-02-08T21:22:14Z
main entity:
{"identifier":"Q27074438","url":"https://www.wikidata.org/entity/Q27074438"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/2c/AMG-517_structure.png","width":1521,"height":796}
fields total:
13
integrity:
15