AM-251 (drug)
id:
am-251-drug-185-296511
title:
AM-251 (drug)
text:
AM-251 is an inverse agonist at the CB1 cannabinoid receptor. AM-251 is structurally very close to rimonabant; both are biarylpyrazole cannabinoid receptor antagonists. In AM-251, the p-chloro group attached to the phenyl substituent at C-5 of the pyrazole ring is replaced with a p-iodo group. The resulting compound exhibits slightly better binding affinity for the CB1 receptor (with a Ki value of 7.5 nM) than rimonabant, which has a Ki value of 11.5 nM, AM-251 is, however, about two-fold more s
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/AM-251_(drug)
date created:
2005-11-21T03:07:01Z
date modified:
2024-09-07T15:53:10Z
main entity:
{"identifier":"Q4652514","url":"https://www.wikidata.org/entity/Q4652514"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e0/AM2512d.png","width":616,"height":445}
fields total:
13
integrity:
16