Aldoxorubicin
id:
aldoxorubicin-247-18090639
title:
Aldoxorubicin
text:
Aldoxorubicin (INNO-206) is a tumor-targeted doxorubicin conjugate in development by CytRx. Specifically, it is the (6-maleimidocaproyl) hydrazone of doxorubicin. Essentially, this chemical name describes doxorubicin attached to an acid-sensitive linker. The proposed mechanism of action is as follows: After administration, aldoxorubicin rapidly binds endogenous circulating albumin through the EMCH linker.
Circulating albumin preferentially accumulates in tumors, bypassing uptake by other non-spe
brand slug:
wiki
category slug:
encyclopedia
description:
Medication
original url:
https://en.wikipedia.org/wiki/Aldoxorubicin
date created:
date modified:
2024-01-19T13:04:08Z
main entity:
{"identifier":"Q19903239","url":"https://www.wikidata.org/entity/Q19903239"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/26/Aldoxorubicin.svg","width":2250,"height":1520}
fields total:
13
integrity:
15