Aldehyde dehydrogenase 18 family, member A1
id:
aldehyde-dehydrogenase-18-family-member-a1-285-9524850
title:
Aldehyde dehydrogenase 18 family, member A1
text:
Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene.
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mu
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_18_family,_member_A1
date created:
date modified:
2023-09-27T15:44:51Z
main entity:
{"identifier":"Q18030979","url":"https://www.wikidata.org/entity/Q18030979"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/8b/Protein_ALDH18A1_PDB_2h5g.png","width":805,"height":463}
fields total:
13
integrity:
15