AEF0117
id:
aef0117-302-16359731
title:
AEF0117
text:
AEF0117 (3β-(4-methoxybenzyloxy)pregn-5-en-20-one) is a compound derived from pregnenolone by Aelis Farma, which acts as a biased allosteric modulator of the cannabinoid CB1 receptor, representing a new class of compounds referred to as CB1-selective signalling-specific inhibitors (CB1-SSi). It binds to an allosteric site on the CB1 receptor and modifies the downstream signalling produced as a result of CB1 activation, preventing CB1 mediated changes to mitogen-activated protein kinase (MAPK) ph
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/AEF0117
date created:
date modified:
2024-02-08T21:39:06Z
main entity:
{"identifier":"Q119872992","url":"https://www.wikidata.org/entity/Q119872992"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/83/AEF0117_structure.png","width":1315,"height":778}
fields total:
13
integrity:
15