ACVR1C

id: acvr1c-239-11721504
title: ACVR1C
text: The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. ACVR1C is a type I receptor for the TGFB family of signaling molecules. ACVR1C transduces signals of Nodal. Nodal binds to ACVR2B and then forms a complex with ACVR1C. These go on to recruit the R-SMADs SMAD2 or SMAD3. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD family transcription factors, which then translocate to the nucleus and interact directly with DNA o
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/ACVR1C
date created:
date modified: 2023-07-22T13:37:21Z
main entity: {"identifier":"Q14905095","url":"https://www.wikidata.org/entity/Q14905095"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/aa/Ideogram_human_chromosome_2.svg","width":474,"height":189}
fields total: 13
integrity: 15

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