ACVR1B
id:
acvr1b-239-6691511
title:
ACVR1B
text:
Activin receptor type-1B is a protein that in humans is encoded by the ACVR1B gene. ACVR1B or ALK-4 acts as a transducer of activin or activin-like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on to recruit the R-SMADs SMAD2 or SMAD3. ACVR1B also transduces signals of nodal, GDF-1, and Vg1; however, unlike activin, they require other coreceptor molecules such as the protein Cripto.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/ACVR1B
date created:
date modified:
2024-03-28T05:48:01Z
main entity:
{"identifier":"Q14905108","url":"https://www.wikidata.org/entity/Q14905108"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b0/Protein_ACVR1B_PDB_1rw8.png","width":859,"height":667}
fields total:
13
integrity:
15