A-971432
id:
a-971432-280-13505508
title:
A-971432
text:
A-971432 is an orally bioavailable selective agonist of sphingosine-1-phosphate receptor 5 (S1PR5) discovered at AbbVie. It was discovered using high-throughput chemistry. S1P5 agonists have been proposed as an innovative mechanism for the treatment of neurodegenerative disorders such as Alzheimer's disease and lysosomal storage disorders such as Niemann–Pick disease. Stimulation of S1PR5 with A-971432 has been shown to preserve blood-brain barrier integrity and exert a therapeutic effect in an
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/A-971432
date created:
date modified:
2024-03-22T10:33:19Z
main entity:
{"identifier":"Q25323800","url":"https://www.wikidata.org/entity/Q25323800"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/9a/A-971432_ball-and-stick.png","width":371,"height":177}
fields total:
13
integrity:
15