8-Oxoguanine
id:
8-oxoguanine-308-708136
title:
8-Oxoguanine
text:
8-Oxoguanine (8-hydroxyguanine, 8-oxo-Gua, or OH8Gua) is one of the most common DNA lesions resulting from reactive oxygen species modifying guanine, and can result in a mismatched pairing with adenine resulting in G to T and C to A substitutions in the genome. In humans, it is primarily repaired by DNA glycosylase OGG1. It can be caused by ionizing radiation, in connection with oxidative metabolism.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/8-Oxoguanine
date created:
date modified:
2023-01-21T17:07:53Z
main entity:
{"identifier":"Q4644284","url":"https://www.wikidata.org/entity/Q4644284"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/3d/8-Oxoguanine.png","width":1177,"height":716}
fields total:
13
integrity:
15