7,8,3'-Trihydroxyflavone
id:
7-8-3-trihydroxyflavone-192-16522618
title:
7,8,3'-Trihydroxyflavone
text:
7,8,3′-Trihydroxyflavone (7,8,3'-THF) is a flavone and small-molecule agonist of TrkB, the main receptor of brain-derived neurotrophic factor (BDNF), that was derived from tropoflavin (7,8-DHF). Relative to tropoflavin, 7,8,3'-THF is 2–3-fold more potent in vitro as a TrkB agonist. 7,3’-Dihydroxyflavone (7,3'-DHF) is also more potent than tropoflavin in vitro, indicating that a 3'-hydroxy group on the B-ring enhances TrkB agonistic activity. 7,8,3'-THF has been tested in vivo and was found to pr
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/7,8,3%27-Trihydroxyflavone
date created:
date modified:
2023-01-30T22:00:49Z
main entity:
{"identifier":"Q25100922","url":"https://www.wikidata.org/entity/Q25100922"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/52/7%2C8%2C3%27-Trihydroxyflavone.svg","width":350,"height":293}
fields total:
13
integrity:
15