6-phosphogluconolactonase
id:
6-phosphogluconolactonase-166-1286892
title:
6-phosphogluconolactonase
text:
6-Phosphogluconolactonase is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the oxidative phase of the pentose phosphate pathway:
- 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate The tertiary structure of 6PGL employs an α/β hydrolase fold, with active site residues clustered on the loops of the α-helices. Based on the crystal structure of the enzyme, the mechanism is proposed to be dependent on pr
brand slug:
wiki
category slug:
encyclopedia
description:
Cytosolic enzyme
original url:
https://en.wikipedia.org/wiki/6-phosphogluconolactonase
date created:
2007-04-08T04:18:06Z
date modified:
2024-08-29T18:05:32Z
main entity:
{"identifier":"Q245505","url":"https://www.wikidata.org/entity/Q245505"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/c/cc/6-phosphogluconolactonase_complexed_with_6-phosphogluconic_acid._PDB-_3E7F.png","width":2400,"height":2400}
fields total:
13
integrity:
16