6-Methylisoxanthopterin

id: 6-methylisoxanthopterin-273-1740750
title: 6-Methylisoxanthopterin
text: 6-Methylisoxanthopterin (6MI) is a base analog for the nucleotide guanine. It is useful as a fluorescent indicator because unlike most other base analogs, quenching does not occur when it is incorporated into a double helix. In fact, it exhibits a 3 to 4-fold increase in quantum yield when it is incorporated into a duplex formation. This allows 6MI to be used to probe the dynamics of DNA or RNA helices using a technique such as fluorescence polarization anisotropy.
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/6-Methylisoxanthopterin
date created:
date modified: 2022-08-25T19:41:11Z
main entity: {"identifier":"Q30314602","url":"https://www.wikidata.org/entity/Q30314602"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4f/6-Methylisoxanthopterin_Structural_Formula_V.1.svg","width":349,"height":200}
fields total: 13
integrity: 15

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