6β-Hydroxy-7α-thiomethylspironolactone
id:
6-hydroxy-7-thiomethylspironolactone-251-10006430
title:
6β-Hydroxy-7α-thiomethylspironolactone
text:
6β-Hydroxy-7α-thiomethylspironolactone (6β-OH-7α-TMS) is a steroidal antimineralocorticoid of the spirolactone group and a major active metabolite of spironolactone. Other important metabolites of spironolactone include 7α-thiospironolactone, 7α-thiomethylspironolactone, and canrenone (SC-9376). Spironolactone is a prodrug with a short terminal half-life of 1.4 hours. The active metabolites of spironolactone have extended terminal half-lives of 13.8 hours for 7α-TMS, 15.0 hours for 6β-OH-7α-TMS,
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/6%CE%B2-Hydroxy-7%CE%B1-thiomethylspironolactone
date created:
date modified:
2022-04-25T03:45:37Z
main entity:
{"identifier":"Q39045972","url":"https://www.wikidata.org/entity/Q39045972"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/1f/6%CE%B2-Hydroxy-7%CE%B1-thiomethylspironolactone.svg","width":1290,"height":1020}
fields total:
13
integrity:
15