5-Hydroxycytosine

id: 5-hydroxycytosine-308-11491912
title: 5-Hydroxycytosine
text: 5-Hydroxycytosine is an oxidized form of cytosine that is associated with an increased frequency of C to T transition mutations, with some C to G transversions. It does not distort the DNA molecule and is readily bypassed by replicative DNA polymerases. It has been shown in vitro to miscode for adenine. 5-hydroxycytosine is imperative for parallel DNA triplex formation, explaining why parallel triplexes form only at pH 6 and below.
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/5-Hydroxycytosine
date created:
date modified: 2022-08-05T14:35:04Z
main entity: {"identifier":"Q21099622","url":"https://www.wikidata.org/entity/Q21099622"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/83/5-hydroxycytosine.svg","width":234,"height":206}
fields total: 13
integrity: 15

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