5'-Guanidinonaltrindole
id:
5-guanidinonaltrindole-194-14256406
title:
5'-Guanidinonaltrindole
text:
5'-Guanidinonaltrindole (5'-GNTI) is an opioid antagonist used in scientific research which is highly selective for the κ opioid receptor. It is 5x more potent and 500 times more selective than the commonly used κ-opioid antagonist norbinaltorphimine. It has a slow onset and long duration of action, and produces antidepressant effects in animal studies. It also increases allodynia by interfering with the action of the κ-opioid peptide dynorphin. In addition to activity at the KOR, 5'-GNTI has be
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/5%27-Guanidinonaltrindole
date created:
date modified:
2022-05-19T11:53:14Z
main entity:
{"identifier":"Q4639531","url":"https://www.wikidata.org/entity/Q4639531"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/1e/5%27-Guanidinonaltrindole.svg","width":177,"height":118}
fields total:
13
integrity:
15