4-Chlorokynurenine
id:
4-chlorokynurenine-301-7543445
title:
4-Chlorokynurenine
text:
L-4-Chlorokynurenine is an orally active small molecule prodrug of 7-chlorokynurenic acid, a NMDA receptor antagonist. It was investigated as a potential rapid-acting antidepressant. AV-101 was discovered at Marion Merrell Dow and its biological activity was explored at University of Maryland. It underwent initial development at Artemis Neuroscience which was acquired by VistaGen in 2003. A phase II clinical trial failed to show any effect over placebo in alleviating treatment-resistant depressi
brand slug:
wiki
category slug:
encyclopedia
description:
Investigational antidepressant compound
original url:
https://en.wikipedia.org/wiki/4-Chlorokynurenine
date created:
date modified:
2024-01-25T19:03:16Z
main entity:
{"identifier":"Q21098923","url":"https://www.wikidata.org/entity/Q21098923"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/60/4-Chlorokynurenine.svg","width":512,"height":265}
fields total:
13
integrity:
15