3-Methyl-19-methyleneandrosta-3,5-dien-17β-ol
id:
3-methyl-19-methyleneandrosta-3-5-dien-17-ol-262-12097986
title:
3-Methyl-19-methyleneandrosta-3,5-dien-17β-ol
text:
3-Methyl-19-methyleneandrosta-3,5-dien-17β-ol is a synthetic, steroidal estrogen and a selective agonist of the ERβ. It was discovered serendipitously and was the lead compound among a series of androsta-3,5-dienes as ERβ ligands. Its affinity (IC50) for the ERβ was found to be 9 nM and it showed 62- and 160-fold binding selectivity for this receptor over the ARTooltip androgen receptor and the ERα, respectively. The EC50 of the compound for the ERβ was found to be 69 nM and its intrinsic activi
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/3-Methyl-19-methyleneandrosta-3,5-dien-17%CE%B2-ol
date created:
date modified:
2023-04-16T12:21:12Z
main entity:
{"identifier":"Q28209808","url":"https://www.wikidata.org/entity/Q28209808"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/0e/3-Methyl-19-methyleneandrosta-3%2C5-dien-17%CE%B2-ol.svg","width":1095,"height":740}
fields total:
13
integrity:
15