3-Keto-5α-abiraterone
id:
3-keto-5-abiraterone-256-15942324
title:
3-Keto-5α-abiraterone
text:
3-Keto-5α-abiraterone, also known as 17-(3-pyridyl)-5α-androst-16-en-3-one, is an active metabolite of abiraterone acetate that has been found to possess androgenic activity and to stimulate prostate cancer progression. It is formed as follows: abiraterone acetate to abiraterone by esterases; abiraterone to Δ4-abiraterone by 3β-hydroxysteroid dehydrogenase/Δ5-4 isomerase; and Δ4-abiraterone to 3-keto-5α-abiraterone by 5α-reductase. 3-Keto-5α-abiraterone may counteract the clinical effectiveness
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/3-Keto-5%CE%B1-abiraterone
date created:
date modified:
2023-11-11T17:44:55Z
main entity:
{"identifier":"Q30647374","url":"https://www.wikidata.org/entity/Q30647374"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/63/3-Keto-5%CE%B1-abiraterone.svg","width":1215,"height":1080}
fields total:
13
integrity:
15