18-Hydroxy-11-deoxycorticosterone
id:
18-hydroxy-11-deoxycorticosterone-239-9621194
title:
18-Hydroxy-11-deoxycorticosterone
text:
18-Hydroxy-11-deoxycorticosterone is an endogenous steroid and a mineralocorticoid. It is a hydroxylated metabolite of 11-deoxycorticosterone. In rats, conversion of 11-deoxycorticosterone into 18-OH-DOC is catalyzed by the CYP11B3 enzyme. In humans, 18-OH-DOC is a weak mineralocorticoid. It may be increased in 17α-hydroxylase (CYP17A1) deficiency, in aldosterone synthase (CYP11B2) deficiency, in primary aldosteronism, and may also indicate a histologic variant of the aldosteronoma. Excessive se
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/18-Hydroxy-11-deoxycorticosterone
date created:
date modified:
2023-04-26T01:04:19Z
main entity:
{"identifier":"Q82939478","url":"https://www.wikidata.org/entity/Q82939478"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/dc/18-Hydroxy-11-deoxycorticosterone.svg","width":163,"height":113}
fields total:
13
integrity:
15