18,19-Dehydrobuprenorphine
id:
18-19-dehydrobuprenorphine-311-7772415
title:
18,19-Dehydrobuprenorphine
text:
18,19-Dehydrobuprenorphine (HS-599) is a didehydro derivative of buprenorphine. It has about twice the potency of buprenorphine. It has produced a long-lasting antinociceptive response in animal tests. 18,19-Dehydrobuprenorphine never induced conditioned place-preference in test animals, unlike buprenorphine and morphine. 18,19-Dehydrobuprenorphine has about three times higher affinity for the μ-opioid receptor but lower affinity for δ- and κ-opioid receptors when compared with buprenorphine.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/18,19-Dehydrobuprenorphine
date created:
date modified:
2023-04-17T11:15:45Z
main entity:
{"identifier":"Q4553712","url":"https://www.wikidata.org/entity/Q4553712"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/34/18%2C19-Dehydrobuprenorphine_Structure.svg","width":595,"height":580}
fields total:
13
integrity:
15