16α-LE2
id:
16-le2-261-1525042
title:
16α-LE2
text:
16α-LE2, or 16α-lactone-estradiol, also known as 3,17β-dihydroxy-19-nor-17α-pregna-1,3,5-(10)-triene-21,16α-lactone, is a synthetic, steroidal estrogen featuring an estradiol core. It is a highly potent and selective agonist of the ERα that is used in scientific research to study the function of the ERα. It has 265-fold higher potency in transactivation assays of the ERα relative to the ERβ and 70-fold preference in binding affinity for the ERα over the ERβ. In rodents, 16α-LE2 has no effect on
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/16%CE%B1-LE2
date created:
date modified:
2023-12-26T13:28:50Z
main entity:
{"identifier":"Q28209297","url":"https://www.wikidata.org/entity/Q28209297"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/27/16aLE2_structure.png","width":544,"height":314}
fields total:
13
integrity:
15