15β-Hydroxycyproterone acetate
id:
15-hydroxycyproterone-acetate-187-18035402
title:
15β-Hydroxycyproterone acetate
text:
15β-Hydroxycyproterone acetate (15β-OH-CPA) is a steroidal antiandrogen and the major metabolite of cyproterone acetate (CPA). It is formed from CPA in the liver by hydroxylation via the cytochrome P450 enzyme CYP3A4. During therapy with CPA, 15β-OH-CPA circulates at concentrations that are approximately twice those of CPA. 15β-OH-CPA has similar or even greater antiandrogen activity compared to CPA. However, it has only about one-tenth of the activity of CPA as a progestogen. 15β-OH-CPA also sh
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/15%CE%B2-Hydroxycyproterone_acetate
date created:
2016-12-09T20:36:55Z
date modified:
2024-09-08T19:37:05Z
main entity:
{"identifier":"Q28209588","url":"https://www.wikidata.org/entity/Q28209588"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/44/15%CE%B2-Hydroxycyproterone_acetate.svg","width":1335,"height":1015}
fields total:
13
integrity:
16